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They can be opinionated and provocative, if needs be. They are not academic pieces but rather provide a broader perspective. These are by invitation only. Book publishers should please send notification of new releases to the Editorial Office ( limit*: 2000Įssays are stimulating articles relevant to our readership. THESE ARE BY INVITATION ONLY.īook reviews are related to one or several books, which surround a topic or viewpoint in neurology. Scientific commentaries are short pieces relating to an article published in the journal. Letters to the Editor are published online only, but are referenced in the printed contents list. Letters to the Editor will be considered only when relating to recent articles published in Brain. Concrete examples from the literature that help to illustrate these points are encouraged. Emphasis should be given to emerging new concepts, findings and theoretical frameworks. They should be accessible to a general neuroscience and clinical neurology readership. Updates are short reviews that focus on a fast-moving, developing or controversial area of research. Your contributions to the literature in this area.Please note: A presubmission enquiry is required prior to submission. Please email to Author list Meta-analyses and systematic reviews of the literature are not considered. Normally these are authored by individuals who have themselves made a significant contribution to the original literature on the topic under review and are acknowledged authorities in the field. Reviews provide a comprehensive and scholarly account of a topic that has direct relevance to clinical neuroscience and that has not recently been covered in the literature. Reports are shorter articles that describe important advances. Studies of single cases that can be readily performed on groups of patients will not be considered. Meta-analyses will not be considered. More detailed studies of single cases may - in rare instances - be considered as a Report (see below) only when they resolve definitively an important problem in the field or when the data lead to a significant conceptual advance. Preliminary reports of work in progress or single case studies are not considered. Studies of normal subjects (including the aged) and normal signalling mechanisms in animals are not considered and will be returned to authors without peer review. Papers that are predominantly methodological or that present hypotheses or models unsupported by original data are not suitable. Animal studies are considered but must demonstrate novel signalling pathways underlying disease or describe novel therapeutic interventions, and have significant clinical relevance. Original articles address neurological diseases and their mechanisms.